Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10344810 | 0.82 | PKM (0.34) | L3MBTL1PKMKDM4ENPC1RAB9A | |
| SCHEMBL27710866 | 0.80 | KMT2A (0.36) | LMNAL3MBTL1PKMKDM4ENPC1 | |
| SCHEMBL2235493 | 0.80 | SMN1; SMN2 (0.42) | NPC1RAB9ASMN1; SMN2POLBHTT | |
| SCHEMBL2538488 | 0.79 | ALOX15 (0.38) | LMNAL3MBTL1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27843264 | 0.79 | — | — | |
| SCHEMBL746118 | 0.79 | PLAU (0.33) | KDM4EPOLBKMT2A | |
| SCHEMBL9490747 | 0.78 | ROCK2 (0.47) | ROCK2LMNAL3MBTL1PKMKDM4E | |
| SCHEMBL137254 | 0.77 | LMNA (0.59) | ROCK2LMNAL3MBTL1PKMKDM4E | |
| SCHEMBL8946061 | 0.77 | LMNA (0.59) | ROCK2LMNAL3MBTL1PKMKDM4E | |
| SCHEMBL2541069 | 0.76 | KMT2A (0.37) | NPC1RAB9ASMN1; SMN2CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |