SCHEMBL9490763

SCHEMBL9490763

O=[C]Nc1ccc(NS(=O)(=O)c2ccccc2)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.69
MEN1 O00255 4/20 0.69
PKM P14618 2/20 0.69
ALDH1A1 P00352 1/20 0.69
KEAP1 Q14145 2/20 0.68
IL1RN P18510 1/20 0.68
ERAP1 Q9NZ08 1/20 0.68
CA12 O43570 2/20 0.61
CA1 P00915 2/20 0.61
CA2 P00918 2/20 0.61
CA9 Q16790 2/20 0.61
HPGD P15428 2/20 0.59
MAPT P10636 1/20 0.59
PGR P06401 1/20 0.59
GAA P10253 1/20 0.56
LMNA P02545 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
NR1I2 O75469 1/20 0.54
HTR6 P50406 1/20 0.54
UQCRB P14927 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28809872 0.95 KMT2A (0.72) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL810795 0.86 KMT2A (0.91) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL20568013 0.84 IL1RN (0.61) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL21836010 0.84 ALDH1A1 (0.68) KMT2AMEN1ALDH1A1CA12CA1
SCHEMBL9001182 0.82 KMT2A (1.00) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL25031372 0.82 KEAP1 (1.00) KMT2AMEN1PKMALDH1A1KEAP1
Phenyl(Phenylsulfonyl)Amine SCHEMBL114765 0.82 KEAP1 (1.00) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL11774264 0.81 KMT2A (0.69) KMT2AMEN1PKMALDH1A1KEAP1
SCHEMBL9489723 0.81 HTR6 (0.56) KMT2AMEN1PKMALDH1A1CA12
SCHEMBL806766 0.81 CA12 (0.85) KMT2AMEN1PKMALDH1A1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5238909-A For preemergence or postemergence use EASTMAN KODAK COMPANY (US) 1993-08-24 US claimed
EP-0476760-A2 4-substituted isoxazole herbicides EASTMAN KODAK COMPANY (US) 1992-03-25 EP claimed
EP-3730306-A1 NON-PHENOLIC COLOUR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2020-10-28 EP disclosed
EP-3630496-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL Papierfabrik August Koehler SE (DE) 2020-04-08 EP disclosed
WO-2018215287-A1 NON-PHENOLIC COLOR DEVELOPER AND HEAT-SENSITIVE RECORDING MATERIAL PAPIERFABRIK AUGUST KOEHLER SE (DE) 2018-11-29 WO disclosed
US-5238909-A For preemergence or postemergence use EASTMAN KODAK COMPANY (US) 1993-08-24 US disclosed
EP-0476760-A2 4-substituted isoxazole herbicides EASTMAN KODAK COMPANY (US) 1992-03-25 EP disclosed