Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9521707 | 1.00 | ALDH1A1 (0.39) | ALDH1A1KMT2AALOX15HSD11B1CYP2D6 | |
| SCHEMBL9520161 | 0.92 | CNR2 (0.41) | ALDH1A1CYP2D6HPGDHTTLMNA | |
| SCHEMBL9491327 | 0.92 | CNR2 (0.41) | ALDH1A1CYP2D6HPGDHTTLMNA | |
| SCHEMBL9490368 | 0.92 | CNR2 (0.41) | ALDH1A1CYP2D6HPGDHTTLMNA | |
| SCHEMBL9490471 | 0.92 | CNR2 (0.41) | ALDH1A1CYP2D6HPGDHTTLMNA | |
| SCHEMBL9490420 | 0.92 | CYP2D6 (0.36) | ALDH1A1CYP2D6HPGDHTTLMNA | |
| SCHEMBL9521837 | 0.92 | CYP2D6 (0.36) | ALDH1A1CYP2D6HPGDHTTLMNA | |
| SCHEMBL9491119 | 0.91 | CYP2D6 (0.36) | ALDH1A1KMT2AHSD11B1CYP2D6HPGD | |
| SCHEMBL9521441 | 0.91 | CYP2D6 (0.36) | ALDH1A1KMT2AHSD11B1CYP2D6HPGD | |
| SCHEMBL9490387 | 0.91 | ALDH1A1 (0.41) | ALDH1A1KMT2ASMN1; SMN2L3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5246950-A | Smooth muscle disorders | RHONE-POULENC SANTE (FR) | 1993-09-21 | — | — | US | disclosed |
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | disclosed |