Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491119 | 1.00 | CYP2D6 (0.36) | CYP2D6HPGDCYP3A4CYP2C8KMT2A | |
| SCHEMBL9521837 | 0.92 | CYP2D6 (0.36) | CYP2D6HPGDCYP3A4ITGA4ITGB7 | |
| SCHEMBL9520161 | 0.92 | CNR2 (0.41) | CYP2D6HPGDITGA4ITGB7ALDH1A1 | |
| SCHEMBL9490420 | 0.92 | CYP2D6 (0.36) | CYP2D6HPGDCYP3A4ITGA4ITGB7 | |
| SCHEMBL9490368 | 0.92 | CNR2 (0.41) | CYP2D6HPGDITGA4ITGB7ALDH1A1 | |
| SCHEMBL9490471 | 0.92 | CNR2 (0.41) | CYP2D6HPGDITGA4ITGB7ALDH1A1 | |
| SCHEMBL9491327 | 0.92 | CNR2 (0.41) | CYP2D6HPGDITGA4ITGB7ALDH1A1 | |
| SCHEMBL9490797 | 0.91 | ALDH1A1 (0.39) | CYP2D6HPGDKMT2AGAAPOLB | |
| SCHEMBL9521707 | 0.91 | ALDH1A1 (0.39) | CYP2D6HPGDKMT2AGAAPOLB | |
| SCHEMBL9521077 | 0.91 | ALDH1A1 (0.41) | KMT2AITGA4ITGB7POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0390693-B1 | THIOFORMAMIDE DERIVATIVES | RHONE-POULENC SANTE (FR) | 1993-08-25 | — | — | EP | disclosed |