⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9491517 | 0.97 | — | — | |
| SCHEMBL21935956 | 0.88 | ALDH1A1 (0.33) | — | |
| SCHEMBL37803 | 0.80 | — | — | |
| SCHEMBL1038813 | 0.80 | THRB (0.31) | — | |
| SCHEMBL3145629 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL7886337 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL8081827 | 0.78 | — | — | |
| SCHEMBL2378730 | 0.78 | LMNA (0.35) | — | |
| SCHEMBL11101672 | 0.78 | KDM4E (0.43) | — | |
| SCHEMBL8081034 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367582-B1 | O-HYDROXYALKYLATION OF 1,1-DIHYDROPERFLUORINATED ALCOHOLS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-02-03 | — | — | EP | claimed |
| EP-0518534-A1 | O-Hydroxyalkylation of 1,1,-dihydro fluorinated alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-12-16 | — | — | EP | claimed |
| EP-0367582-A1 | O-hydroxyalkylation of 1,1-dihydroperfluorinated alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-09 | — | — | EP | claimed |
| US-4906792-A | O-hydroxyalkylation of 1,1-dihydroperfluorinated alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-06 | — | — | US | claimed |
| EP-0367582-B1 | O-HYDROXYALKYLATION OF 1,1-DIHYDROPERFLUORINATED ALCOHOLS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0518534-A1 | O-Hydroxyalkylation of 1,1,-dihydro fluorinated alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-12-16 | — | — | EP | disclosed |
| US-5157159-A | Reacting alcohols with alkylene carbonate in the presence of nitrogen base catalyst | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1992-10-20 | — | — | US | disclosed |
| EP-0367582-A1 | O-hydroxyalkylation of 1,1-dihydroperfluorinated alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-05-09 | — | — | EP | disclosed |
| US-4906792-A | O-hydroxyalkylation of 1,1-dihydroperfluorinated alcohols | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-03-06 | — | — | US | disclosed |