SCHEMBL7886337

SCHEMBL7886337

CC(O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
THRB P10828 1/20 0.35
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2378730 1.00 LMNA (0.35) LMNATHRBCA1CA2MMP1
SCHEMBL11588700 1.00 LMNA (0.35) LMNATHRBCA1CA2MMP1
SCHEMBL7885479 1.00 LMNA (0.35) LMNATHRBCA1CA2MMP1
SCHEMBL3145629 1.00 LMNA (0.35) LMNATHRBCA1CA2MMP1
SCHEMBL7640241 1.00 LMNA (0.35) LMNATHRBCA1CA2MMP1
SCHEMBL970481 1.00 LMNA (0.35) LMNATHRBCA1CA2MMP1
SCHEMBL29152257 0.97 LMNA (0.33) LMNATHRB
SCHEMBL1038813 0.97 THRB (0.31) LMNATHRBCA1CA2MMP1
Acetic Acid SCHEMBL29256055 0.89 THRB (0.43) THRBCA1CA2MMP1MMP2
SCHEMBL198026 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112457762-A High-adhesion fluorine-containing hydrophobic polyurethane transparent protective coating and preparation and use methods thereof 中国科学院长春应用化学研究所 2021-03-09 CN claimed
CN-110564280-A Double-component fluorine-containing hydrophobic coating and preparation and use methods thereof 国电新能源技术研究院有限公司 2019-12-13 CN claimed
WO-1996037540-A1 FOAMABLE COMPOSITION CONTAINING UNSATURATED PERFLUOROCHEMICAL BLOWING AGENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-11-28 WO claimed
US-4455247-A FLUORINATED ALCOHOL, AND A HIGH BOILING ELETRON DONATING ABSORBENT; SANYO ELECTRIC CO., LTD. (JP) 1984-06-19 US claimed
EP-0048281-A1 COMPOSITION FOR ABSORPTION REFRIGERATOR Sanyo Electric Co., Ltd (JP) 1982-03-31 EP claimed
US-12576297-B2 Apparatus and methods for sonochemical degradation of per- and polyfluoroalkyl substances THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-03-17 US disclosed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
US-20240059860-A1 METHODS AND SYSTEMS FOR DESTRUCTION OF SYNTHETIC PER- AND POLYFLUORO COMPOUNDS CHZ TECHNOLOGIES, LLC 2024-02-22 US disclosed
US-11261373-B2 Preparation method of supercritical carbon dioxide thickener for tight oil and gas reservoir SOUTHWEST PETROLEUM UNIVERSITY (CN) 2022-03-01 US disclosed
CN-112457762-A High-adhesion fluorine-containing hydrophobic polyurethane transparent protective coating and preparation and use methods thereof 中国科学院长春应用化学研究所 2021-03-09 CN disclosed
CN-112239956-A Composition of fluorine polyurethane for water and oil repellent and preparation method thereof 漳州丰笙新材料有限公司 2021-01-19 CN disclosed
US-20200385631-A1 Preparation Method of Supercritical Carbon Dioxide Thickener for Tight Oil and Gas Reservoir SOUTHWEST PETROLEUM UNIVERSITY 2020-12-10 US disclosed
WO-1996037540-A1 FOAMABLE COMPOSITION CONTAINING UNSATURATED PERFLUOROCHEMICAL BLOWING AGENT MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-11-28 WO disclosed
EP-0710262-A1 ORGANIC AEROGELS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-05-08 EP disclosed
US-5484818-A Organic aerogels IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1996-01-16 US disclosed
US-5393799-A Reacting reaction product of excess polyisocyanate and fluorinated isocyanate-reactive compound with polyfunctional reactive composition under foam-forming conditions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-02-28 US disclosed
WO-1995003358-A1 ORGANIC AEROGELS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1995-02-02 WO disclosed
EP-0605105-A1 Process for rigid foams IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-07-06 EP disclosed
US-4455247-A FLUORINATED ALCOHOL, AND A HIGH BOILING ELETRON DONATING ABSORBENT; SANYO ELECTRIC CO., LTD. (JP) 1984-06-19 US disclosed
EP-0048281-A1 COMPOSITION FOR ABSORPTION REFRIGERATOR Sanyo Electric Co., Ltd (JP) 1982-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200385631-A1 Preparation Method of Supercritical Carbon Dioxide Thickener for Tight Oil and Gas Reservoir DGKA, DGKG, DGKI LMNA 1516/4885THRB 3071/4885CA1 2046/4885
US-11261373-B2 Preparation method of supercritical carbon dioxide thickener for tight oil and gas reservoir DGKA, DGKG, DGKI LMNA 2100/4885THRB 3146/4885CA1 516/4885
US-12576297-B2 Apparatus and methods for sonochemical degradation of per- and polyfluoroalkyl substances PFAS, PIEZO1, UFL1 LMNA 1329/4885THRB 1680/4885CA1 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.