Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17546133 | 0.87 | TRPV4 (0.39) | TRPV4CYP11B1CYP11B2VCAM1KHK | |
| SCHEMBL157603 | 0.85 | CES2 (0.42) | TRPV4CYP11B1CYP11B2CES2CES1 | |
| SCHEMBL17545813 | 0.81 | TRPV4 (0.35) | TRPV4CYP11B1CYP11B2VCAM1KHK | |
| SCHEMBL10877908 | 0.79 | TRPV4 (0.46) | TRPV4CYP11B1CYP11B2VCAM1KHK | |
| SCHEMBL1996117 | 0.78 | TRPV4 (0.41) | TRPV4CYP11B1CYP11B2CES2CES1 | |
| SCHEMBL16122304 | 0.77 | TSHR (0.37) | TRPV4CYP11B1CYP11B2VCAM1TTR | |
| SCHEMBL16122643 | 0.77 | GRM5 (0.42) | TRPV4CYP11B2VCAM1KHKALDH1A1 | |
| SCHEMBL11981507 | 0.77 | TRPV4 (0.38) | TRPV4CYP11B1CYP11B2VCAM1KHK | |
| SCHEMBL16122332 | 0.77 | TTR (0.50) | TRPV4CYP11B1CYP11B2VCAM1TTR | |
| SCHEMBL807520 | 0.77 | TRPV4 (0.34) | TRPV4CYP11B1CYP11B2VCAM1KHK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12497363-B2 | Isophthalonitrile compound, luminescent material and luminescent element using the same | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2025-12-16 | — | — | US | disclosed |
| EP-3985081-B1 | ISOPHTHALONITRILE COMPOUNDS, LUMINESCENT MATERIAL, AND LUMINESCENT ELEMENT INCLUDING SAME | UNIV KYUSHU NAT UNIV CORP (JP) | 2025-03-12 | — | — | EP | disclosed |
| CN-113939501-B | Isophthalonitrile compound, light-emitting material, and light-emitting element using same | 国立大学法人九州大学 | 2024-10-22 | — | — | CN | disclosed |
| US-20220242822-A1 | ISOPHTHALONITRILE COMPOUND, LUMINESCENT MATERIAL AND LUMINESCENT ELEMENT USING THE SAME | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2022-08-04 | — | — | US | disclosed |
| EP-3985081-A1 | ISOPHTHALONITRILE COMPOUNDS, LUMINESCENT MATERIAL, AND LUMINESCENT ELEMENT INCLUDING SAME | Kyushu University, National University Corporation (JP) | 2022-04-20 | — | — | EP | disclosed |
| CN-113939501-A | Isophthalonitrile compound, light-emitting material, and light-emitting element using same | 国立大学法人九州大学 | 2022-01-14 | — | — | CN | disclosed |
| WO-2020250851-A1 | ISOPHTHALONITRILE COMPOUNDS, LUMINESCENT MATERIAL, AND LUMINESCENT ELEMENT INCLUDING SAME | 国立大学法人九州大学 | 2020-12-17 | — | — | WO | disclosed |
| EP-0307897-B1 | TRIFLUOROBENZENE COMPOUNDS AND PROCESS FOR PRODUCING THE SAME | SDS Biotech K.K. (JP) | 1993-03-17 | — | — | EP | disclosed |
| US-5068411-A | Hydrolysis of 2,4,5-trifluoroisophthalonitrile in the presence of sulfuric acid to form 2,4,5-trifluoroisophthalic acid | SDS BIOTECH K.K. (JP) | 1991-11-26 | — | — | US | disclosed |
| US-5021605-A | Chemical intermediates | SDS BIOTECH K.K. (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4925966-A | DEFLUORINATION OF TETRAFLUOROISOPHTHALONITRILE WITH METAL HYDRIDE TO MAKE 2,4,5-TRIFLURORISOPHTHALONITRILE | SDS BIOTECH K.K. (JP) | 1990-05-15 | — | — | US | disclosed |
| EP-0307897-A1 | Trifluorobenzene compounds and process for producing the same | SDS Biotech K.K. (JP) | 1989-03-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12497363-B2 | Isophthalonitrile compound, luminescent material and luminescent element using the same | EPB41L2, NMRAL1, HNRNPH3 | TRPV4 938/4885CYP11B1 3373/4885CYP11B2 3240/4885 |
| US-20220242822-A1 | ISOPHTHALONITRILE COMPOUND, LUMINESCENT MATERIAL AND LUMINESCENT ELEMENT USING THE SAME | EPB41L2, NMRAL1, HNRNPH3 | TRPV4 938/4885CYP11B1 3373/4885CYP11B2 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.