Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.30 |
| ▸ | STAT3 | P40763 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6896856 | 0.80 | CYP2C9 (0.46) | CACNA1GCACNA1HCACNA1IACACBKMT2A | |
| SCHEMBL10592324 | 0.79 | ACACB (0.35) | ACACBKMT2AGPR88 | |
| SCHEMBL9292192 | 0.79 | KMT2A (0.36) | ACACBKMT2AMAPTTHRB | |
| SCHEMBL9491245 | 0.78 | ACACB (0.33) | ACACBMAPT | |
| SCHEMBL9491249 | 0.78 | ACACB (0.34) | ACACBKMT2AMAPTTHRB | |
| SCHEMBL9491241 | 0.78 | ACACB (0.34) | ACACBKMT2AMAPTTHRB | |
| SCHEMBL13025717 | 0.73 | CYP2C9 (0.42) | CACNA1GCACNA1HCACNA1IACACBKMT2A | |
| SCHEMBL9490604 | 0.73 | RAB9A (0.34) | ACACBKMT2AMAPTTHRB | |
| SCHEMBL10591720 | 0.73 | ALOX5 (0.35) | ACACBGPR88 | |
| SCHEMBL10590106 | 0.73 | ACACB (0.34) | ACACBGPR88 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343487-B1 | CYCLOHEXYL ESTERS OF ALPHA-FLUORO/CARBOXYLIC ACIDS | F. HOFFMANN-LA ROCHE AG (CH) | 1993-01-20 | — | — | EP | disclosed |
| EP-0343487-A1 | Cyclohexyl esters of alpha-fluoro/carboxylic acids | F. HOFFMANN-LA ROCHE AG (CH) | 1989-11-29 | — | — | EP | disclosed |