Malonic Acid

Malonic Acid

SCHEMBL9491887

O=C(O)C=CC(CO)(CO)CCO.O=C(O)CC(=O)O

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LDHA P00338 1/20 0.35
SRR Q9GZT4 1/20 0.35
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succinic Acid SCHEMBL1656097 0.89 LMNA (0.35)
Itaconate SCHEMBL9490728 0.87 ALOX15 (0.53) ALOX15HSD17B10
Glutarate SCHEMBL9491763 0.85 CAMK2A (0.40)
Adipic Acid SCHEMBL9492333 0.85 GPR84 (0.42) ALOX15HSD17B10
Sebacic Acid SCHEMBL9493046 0.84 GPR84 (0.45) ALOX15HSD17B10
SCHEMBL16207460 0.76 TSHR (0.34)
Maleic Anhydride SCHEMBL9492190 0.76
Succinic Acid SCHEMBL3195268 0.75 LMNA (0.41)
SCHEMBL8859521 0.70 TSHR (0.38)
SCHEMBL10761024 0.69 TSHR (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232033-B1 TRANSPARENT ELECTRICALLY CONDUCTIVE PLASTIC MOLDED ARTICLES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-04-07 EP disclosed
EP-0174373-B1 PROCESS FOR PRODUCING HEAT-RESISTANT RESIN MOLDINGS HAVING EXCELLENT ABRASION RESISTANCE MITSUBISHI RAYON CO., LTD. (JP) 1989-08-02 EP disclosed
US-4737409-A Heat-resistant resin molded article with excellent abrasion resistance and process for producing the same MITSUBISHI RAYON CO., LTD. (JP) 1988-04-12 US disclosed
US-4734319-A TIN OXIDE AND HARDENING RESIN SUMITOMO CHEMICAL CO., LTD. (JP) 1988-03-29 US disclosed
US-4689243-A A POLYDIMETHYLGLUTARIMIDE RESIN COATED WITH A CURED RESIN OF POLY(METH)ACRYLOYLOXY-GROUP CONTAINING MONOMER MITSUBISHI RAYON CO., LTD. (JP) 1987-08-25 US disclosed
EP-0232033-A2 Transparent electrically conductive plastic molded articles SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-12 EP disclosed
EP-0174373-A1 PROCESS FOR PRODUCING HEAT-RESISTANT RESIN MOLDINGS HAVING EXCELLENT ABRASION RESISTANCE MITSUBISHI RAYON CO., LTD. (JP) 1986-03-19 EP disclosed
EP-0057906-B1 COATING COMPOSITION AND PROCESS FOR PREPARING SYNTHETIC RESIN SHAPED ARTICLES BY USING SAME MITSUBISHI RAYON CO., LTD. (JP) 1985-05-29 EP disclosed
EP-0037978-B1 COATING COMPOSITION AND PROCESS FOR PREPARING SYNTHETIC RESIN SHAPED ARTICLES BY USING SAME MITSUBISHI RAYON CO., LTD. (JP) 1985-03-20 EP disclosed
US-4388345-A ULTRAVIOLET-INDUCED POLYMERIZATION MITSUBISHI RAYON COMPANY LTD. (JP) 1983-06-14 US disclosed
US-4367245-A WEATHERPROOFING MITSUBISHI RAYON COMPANY, LTD. (JP) 1983-01-04 US disclosed
EP-0057906-A1 Coating composition and process for preparing synthetic resin shaped articles by using same MITSUBISHI RAYON CO., LTD. (JP) 1982-08-18 EP disclosed
EP-0037978-A2 Coating composition and process for preparing synthetic resin shaped articles by using same MITSUBISHI RAYON CO., LTD. (JP) 1981-10-21 EP disclosed