Itaconate

Itaconate

SCHEMBL9490728

C=C(CC(=O)O)C(=O)O.O=C(O)C=CC(CO)(CO)CCO

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL9491887 0.87 LDHA (0.35) ALOX15HSD17B10
Succinic Acid SCHEMBL1656097 0.80 LMNA (0.35)
Glutarate SCHEMBL9491763 0.77 CAMK2A (0.40)
Adipic Acid SCHEMBL9492333 0.77 GPR84 (0.42) ALOX15HSD17B10
Sebacic Acid SCHEMBL9493046 0.76 GPR84 (0.45) ALOX15HSD17B10
Itaconate SCHEMBL676005 0.75 ALOX15 (0.74) ALOX15HSD17B10
Itaconate SCHEMBL676003 0.75 ALOX15 (0.74) ALOX15HSD17B10
Itaconate SCHEMBL20487586 0.75 ALOX15 (0.74) ALOX15HSD17B10
Itaconate SCHEMBL271206 0.75 ALOX15 (0.74) ALOX15HSD17B10
Itaconate SCHEMBL7908952 0.74 ALOX15 (0.87) ALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0232033-B1 TRANSPARENT ELECTRICALLY CONDUCTIVE PLASTIC MOLDED ARTICLES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-04-07 EP disclosed
EP-0174373-B1 PROCESS FOR PRODUCING HEAT-RESISTANT RESIN MOLDINGS HAVING EXCELLENT ABRASION RESISTANCE MITSUBISHI RAYON CO., LTD. (JP) 1989-08-02 EP disclosed
US-4737409-A Heat-resistant resin molded article with excellent abrasion resistance and process for producing the same MITSUBISHI RAYON CO., LTD. (JP) 1988-04-12 US disclosed
US-4734319-A TIN OXIDE AND HARDENING RESIN SUMITOMO CHEMICAL CO., LTD. (JP) 1988-03-29 US disclosed
EP-0232033-A2 Transparent electrically conductive plastic molded articles SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-08-12 EP disclosed