SCHEMBL949285

SCHEMBL949285

Oc1cccc(O)c1-c1ccccc1-c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.65
HSD17B10 Q99714 5/20 0.65
HPGD P15428 4/20 0.65
BCL2L1 Q07817 1/20 0.65
BACE1 P56817 3/20 0.54
HDAC4 P56524 2/20 0.50
HDAC2 Q92769 2/20 0.50
HDAC8 Q9BY41 2/20 0.50
HDAC6 Q9UBN7 1/20 0.50
HNF4A P41235 1/20 0.50
MAOA P21397 3/20 0.48
MAPT P10636 4/20 0.46
ALOX15 P16050 3/20 0.46
TDP1 Q9NUW8 3/20 0.46
MAPK1 P28482 2/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
ALOX5 P09917 1/20 0.46
TSHR P16473 1/20 0.46
MAOB P27338 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9236958 0.98 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL11786820 0.91 ALDH1A1 (0.60) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL12023128 0.88 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL30223649 0.88 ALDH1A1 (0.68) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL18150 0.86 ALDH1A1 (0.65) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL8644875 0.86 HDAC4 (0.50) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL8158458 0.86 ALDH1A1 (0.54) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL23329593 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL12023162 0.84 HPGD (0.70) ALDH1A1HSD17B10HPGDBCL2L1BACE1
SCHEMBL30028001 0.84 ALDH1A1 (0.62) ALDH1A1HSD17B10HPGDBCL2L1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6143379-A Polymer laminates having increased hiding power CLARIANT GMBH (DE) 2000-11-07 US claimed
EP-0375287-A2 Aromatic polymers NORTH WEST WATER GROUP PLC (GB) 1990-06-27 EP claimed
CN-119193074-A Composition for forming adhesive layer, laminate, method for producing laminate, and method for treating laminate 日铁化学材料株式会社 2024-12-27 CN disclosed
EP-4053095-B1 METHOD FOR PRODUCING SODIUM SALT OF PHENOLIC COMPOUND AND BISPHOSPHITE COMPOUND MITSUBISHI CHEM CORP (JP) 2024-07-10 EP disclosed
EP-4053095-A1 METHOD FOR PRODUCING SODIUM SALT OF PHENOLIC COMPOUND AND BISPHOSPHITE COMPOUND Mitsubishi Chemical Corporation (JP) 2022-09-07 EP disclosed
US-20220251122-A1 METHOD FOR PRODUCING SODIUM SALT OF PHENOL COMPOUND AND BISPHOSPHITE COMPOUND MITSUBISHI CHEMICAL CORPORATION (JP) 2022-08-11 US disclosed
CN-110713588-B Hardmask composition, hardmask layer and method of forming pattern 三星SDI株式会社 2022-08-09 CN disclosed
CN-114763412-A High-efficiency preparation method of phosphonate polymer and application of phosphonate polymer in high-temperature fuel cell 天津师范大学 2022-07-19 CN disclosed
CN-114616221-A Process for producing sodium salt of phenol compound and bisphosphite compound 三菱化学株式会社 2022-06-10 CN disclosed
US-11214678-B2 Hardmask composition, hardmask layer and method of forming patterns SAMSUNG SDI CO., LTD. (KR) 2022-01-04 US disclosed
CN-108368217-B Oxazine compound, composition and cured product DIC株式会社 2021-05-07 CN disclosed
US-5037936-A Bis(acid chloride) terminated polyaryl ether ketone oligomer AMOCO CORPORATION (US) 1991-08-06 US disclosed
US-5011623-A Nonlinear optical material and nonlinear optical device CANON KABUSHIKI KAISHA (JP) 1991-04-30 US disclosed
US-4959423-A IMPROVED CRYSTALLIZATION RATES AMOCO CORPORATION (US) 1990-09-25 US disclosed
US-4910289-A Crystal structure; blend with poly(arylene sulfide) AMOCO CORPORATION (US) 1990-03-20 US disclosed
EP-0351832-A2 Nonlinear optical material and nonlinear optical device CANON KABUSHIKI KAISHA (JP) 1990-01-24 EP disclosed
EP-0346911-A1 Display medium, display method and display apparatus CANON KABUSHIKI KAISHA (JP) 1989-12-20 EP disclosed
US-4861915-A Poly (aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1989-08-29 US disclosed
EP-0292244-A2 Polymeric liquid crystal composition and liquid crystal device CANON KABUSHIKI KAISHA (JP) 1988-11-23 EP disclosed
US-4786694-A Poly(aryl ether ketone) block copolymers AMOCO CORPORATION (US) 1988-11-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220251122-A1 METHOD FOR PRODUCING SODIUM SALT OF PHENOL COMPOUND AND BISPHOSPHITE COMPOUND SLC20A2, SOST, SLC20A1 ALDH1A1 3616/4885HSD17B10 1554/4885HPGD 1319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.