Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | FDPS | P14324 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493223 | 0.83 | ALOX15 (0.37) | LMNAHSD17B10TSHRTDP1ALOX15 | |
| SCHEMBL4435639 | 0.81 | GAA (0.45) | LMNAHSD17B10ALDH1A1GAA | |
| SCHEMBL28889809 | 0.77 | LMNA (0.44) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL27907896 | 0.76 | LMNA (0.52) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL224525 | 0.76 | LMNA (0.52) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL9446509 | 0.75 | ALOX15 (0.42) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL868219 | 0.74 | — | — | |
| SCHEMBL30718877 | 0.73 | LMNA (0.46) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL30552233 | 0.73 | LMNA (0.48) | LMNAHSD17B10TSHRCYP3A4NFKB1 | |
| SCHEMBL28870458 | 0.72 | LMNA (0.48) | LMNAHSD17B10TSHRCYP3A4NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5179223-A | Reacting primary amine, urea and oxime | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |