Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 6/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10824100 | 0.84 | BCHE (0.38) | GPR35CYP1A2CYP3A4FABP3CYP2D6 | |
| SCHEMBL9492598 | 0.78 | ELANE (0.44) | CYP3A4MEN1KMT2APARP1MAPT | |
| SCHEMBL9493428 | 0.77 | GPR35 (0.37) | GPR35MEN1KMT2APARP1MAPT | |
| SCHEMBL11100280 | 0.76 | F2RL3 (0.36) | GPR35PARP1MAPT | |
| SCHEMBL9495375 | 0.74 | PPARA (0.44) | GPR35CYP3A4MEN1KMT2AHTT | |
| SCHEMBL21144535 | 0.74 | MAPT (0.39) | CYP3A4MEN1KMT2AHTTMAPT | |
| SCHEMBL9492530 | 0.72 | AHR (0.36) | GPR35CYP1A2CYP3A4FABP3CYP2D6 | |
| SCHEMBL10507026 | 0.71 | BCHE (0.37) | CYP1A2CYP2D6MEN1KMT2AHTT | |
| SCHEMBL10505509 | 0.71 | BCHE (0.37) | CYP1A2CYP2D6MEN1KMT2AHTT | |
| SCHEMBL9495383 | 0.70 | NT5E (0.39) | GPR35MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113432-B1 | CHLOROMETHYL QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | ALKALOIDA VEGYéSZETI GYáR (HU) | 1993-03-17 | — | — | EP | claimed |
| EP-0113432-A1 | Chloromethyl quinoline derivatives, process for their preparation and their use | ALKALOIDA VEGYéSZETI GYáR (HU) | 1984-07-18 | — | — | EP | claimed |