Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11100280 | 0.88 | F2RL3 (0.36) | GPR35LMNAMAPTPARP1SLC40A1 | |
| SCHEMBL10824100 | 0.81 | BCHE (0.38) | GPR35HRH4MEN1KMT2ANT5E | |
| SCHEMBL9493433 | 0.77 | GPR35 (0.36) | GPR35MAPTMEN1KMT2APARP1 | |
| SCHEMBL9495375 | 0.75 | PPARA (0.44) | GPR35LMNAMAPTNR4A2MEN1 | |
| SCHEMBL21144535 | 0.75 | MAPT (0.39) | LMNAMAPTMEN1KMT2ANT5E | |
| SCHEMBL9493152 | 0.74 | NR4A2 (0.46) | LMNAMAPTNR4A2MEN1KMT2A | |
| SCHEMBL9492602 | 0.74 | LMNA (0.64) | LMNAMAPTNT5EL3MBTL1 | |
| SCHEMBL9492598 | 0.72 | ELANE (0.44) | MAPTNR4A2MEN1KMT2APARP1 | |
| SCHEMBL9492527 | 0.71 | LMNA (0.36) | GPR35LMNAMAPTNR4A2MEN1 | |
| SCHEMBL9492838 | 0.70 | LMNA (0.46) | LMNAMAPTKMT2APARP1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113432-B1 | CHLOROMETHYL QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | ALKALOIDA VEGYéSZETI GYáR (HU) | 1993-03-17 | — | — | EP | claimed |
| EP-0113432-A1 | Chloromethyl quinoline derivatives, process for their preparation and their use | ALKALOIDA VEGYéSZETI GYáR (HU) | 1984-07-18 | — | — | EP | claimed |