Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21144535 | 0.87 | MAPT (0.39) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11099839 | 0.84 | MAPT (0.35) | PPARAMAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL9492598 | 0.79 | ELANE (0.44) | MAPTL3MBTL1KMT2AMEN1KDM4E | |
| SCHEMBL20562217 | 0.79 | CYP3A4 (0.37) | MAPTL3MBTL1KDM4EPKMHTT | |
| SCHEMBL9493152 | 0.78 | NR4A2 (0.46) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9493428 | 0.75 | GPR35 (0.37) | MAPTGPR35L3MBTL1KMT2AMEN1 | |
| SCHEMBL11099657 | 0.75 | CRHR1 (0.49) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9493489 | 0.75 | ALDH1A1 (0.43) | NPSR1L3MBTL1ALDH1A1KDM4EHTT | |
| SCHEMBL11100280 | 0.74 | F2RL3 (0.36) | MAPTGPR35LMNASLC40A1 | |
| SCHEMBL9492503 | 0.74 | CYP3A4 (0.40) | MAPTNPSR1L3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113432-B1 | CHLOROMETHYL QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE | ALKALOIDA VEGYéSZETI GYáR (HU) | 1993-03-17 | — | — | EP | claimed |
| EP-0113432-A1 | Chloromethyl quinoline derivatives, process for their preparation and their use | ALKALOIDA VEGYéSZETI GYáR (HU) | 1984-07-18 | — | — | EP | claimed |