Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.30 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493428 | 0.88 | GPR35 (0.37) | GPR35LMNAMAPTSLC40A1PIM1 | |
| SCHEMBL9493433 | 0.76 | GPR35 (0.36) | GPR35MAPTPARP1 | |
| SCHEMBL11099657 | 0.74 | CRHR1 (0.49) | LMNAMAPTCRHR1PARP1 | |
| SCHEMBL9495375 | 0.74 | PPARA (0.44) | GPR35LMNAMAPTSLC40A1 | |
| SCHEMBL21144535 | 0.74 | MAPT (0.39) | LMNAMAPT | |
| SCHEMBL10824100 | 0.73 | BCHE (0.38) | GPR35 | |
| SCHEMBL9492602 | 0.72 | LMNA (0.64) | LMNAMAPT | |
| SCHEMBL9492598 | 0.71 | ELANE (0.44) | MAPTCRHR1PARP1 | |
| SCHEMBL9493152 | 0.69 | NR4A2 (0.46) | LMNAMAPTCRHR1PIM1PARP1 | |
| SCHEMBL9492838 | 0.69 | LMNA (0.46) | LMNAMAPTPIM1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0113432-A1 | Chloromethyl quinoline derivatives, process for their preparation and their use | ALKALOIDA VEGYéSZETI GYáR (HU) | 1984-07-18 | — | — | EP | claimed |