Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.43 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816603 | 0.87 | CYP3A4 (0.54) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL9044260 | 0.81 | KMT2A (0.59) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL7616111 | 0.80 | CYP3A4 (0.51) | ALDH1A1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL9493555 | 0.80 | RAB9A (0.57) | ALDH1A1KMT2AMEN1MAPTHPGD | |
| SCHEMBL7616104 | 0.79 | ALDH1A1 (0.49) | ALDH1A1KMT2ACYP3A4MAPTHPGD | |
| SCHEMBL253535 | 0.78 | CYP3A4 (0.77) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL5972595 | 0.78 | KMT2A (0.56) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL5826299 | 0.78 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL11552687 | 0.78 | L3MBTL1 (0.54) | ALDH1A1KMT2AMEN1CYP3A4MAPT | |
| SCHEMBL31370710 | 0.77 | KMT2A (0.55) | ALDH1A1KMT2AMEN1CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248805-A | Radiation-senstive, ethylenically unsaturated, copolymerizable compounds and their preparation | BASF AKTIENGESELLSCHAFT (DE) | 1993-09-28 | — | — | US | disclosed |