SCHEMBL9504915

SCHEMBL9504915

CCN(CC)C(=O)n1cnc(S(=O)(=O)Oc2cccnc2)n1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CCNC P24863 1/20 0.40
CDK8 P49336 1/20 0.40
MAPT P10636 3/20 0.39
KMT2A Q03164 3/20 0.39
CHRNB2 P17787 4/20 0.39
CHRNA4 P43681 4/20 0.39
TRPM8 Q7Z2W7 1/20 0.38
ALDH1A1 P00352 2/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
P2RX4 Q99571 1/20 0.36
LMNA P02545 3/20 0.36
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.35
HTT P42858 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9492475 0.87 MGLL (0.42) KMT2ATRPM8ALDH1A1TSHRP2RX4
SCHEMBL9492617 0.82 KMT2A (0.40) MAPTKMT2ATRPM8TP53LMNA
SCHEMBL9495195 0.81 KMT2A (0.40) MAPTKMT2ATRPM8ALDH1A1TP53
SCHEMBL9494256 0.81 PPARG (0.38) TRPM8
SCHEMBL9494430 0.81 YAP1 (0.40) MAPTKMT2ATRPM8LMNAHPGD
SCHEMBL9491411 0.79 ALDH1A1 (0.35) MAPTKMT2AALDH1A1TSHRLMNA
SCHEMBL9493429 0.76 DPP4 (0.38) KMT2AALDH1A1P2RX4LMNAKDM4E
SCHEMBL9542985 0.73 DPP4 (0.42) MAPTKMT2AALDH1A1P2RX4LMNA
SCHEMBL9015551 0.71 DPP4 (0.40) MAPTKMT2AALDH1A1P2RX4LMNA
SCHEMBL9544526 0.71 DPP4 (0.40) KMT2AALDH1A1P2RX4LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5140150-A None JP disclosed
JP-H05140150-A TRIAZOLE DERIVATIVE AND HERBICIDE HOKKO CHEM IND CO LTD 1993-06-08 JP disclosed