Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21475275 | 0.78 | NFKB1 (0.36) | NPSR1MAPTRAB9ANFKB1NFKB2 | |
| SCHEMBL949460 | 0.76 | MAOB (0.51) | NPSR1MAPTMAOBMAPK1NOD2 | |
| SCHEMBL18808263 | 0.74 | NFKB1 (0.38) | NFKB1NFKB2RELAALOX5 | |
| SCHEMBL21898228 | 0.74 | MAPT (0.43) | MAPTMAPK1RAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL18535608 | 0.71 | ESR1 (0.52) | MAPTRAB9ANPC1ALDH1A1 | |
| SCHEMBL2182312 | 0.70 | CA2 (0.44) | MAPTMAOBRAB9ASMN1; SMN2NFKB1 | |
| SCHEMBL7114668 | 0.70 | TRPA1 (0.42) | MAOBNFKB1NFKB2RELA | |
| SCHEMBL2179159 | 0.69 | ESR1 (0.52) | NFKB1NFKB2RELA | |
| SCHEMBL9270633 | 0.69 | ALOX5 (0.50) | MAPTMAOBRAB9AMRGPRX4MAOA | |
| SCHEMBL18773616 | 0.69 | POLB (0.38) | MAPTRAB9ASMN1; SMN2NFKB1NFKB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7875735-B2 | such as haginin E, equol, daidzein, formononetin; dealkylation, hydroboration, oxidation in presence of base, oxidation-dehydrogenation using 2,3-dichloro-5,6-dicyanobenzoquinone, and deprotecting | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-01-25 | — | — | US | disclosed |
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298581-A1 | Processes for Preparing Isoflavonoids using 7-benzyloxy-3-(4-methoxyphenyl)-2H-1-benzopyran as a Starting Material | EGLN2, HABP2, CYP8B1 | NPSR1 2625/4885MAPT 4056/4885MAOB 1773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.