SCHEMBL2937052

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2742798	0.91	MAPT (0.39)	RARARARGRARBALOX5NR1H4
	SCHEMBL4556762	0.83	CYP2D6 (0.42)	RARARARGRARBALOX5ALDH1A1
	SCHEMBL12946430	0.80	ALOX5 (0.43)	RARARARGRARBALOX5NR1H4
	SCHEMBL2328053	0.78	ALOX5 (0.41)	ALOX5NR1H4PTGS2ROR1MAOB
	SCHEMBL949460	0.77	MAOB (0.51)	ALOX5MAOBMAOAALDH1A1MAPT
	SCHEMBL4549088	0.77	MAOB (0.35)	ALOX5NR1H4MAOBMAOAALDH1A1
	SCHEMBL4556779	0.77	THRA (0.37)	ALOX5NR1H4PTPN1ROR1MAOB
	SCHEMBL1962780	0.75	MAOB (0.51)	ALOX5MAOBMAOAALDH1A1MAPT
	SCHEMBL952469	0.73	NR1H4 (0.54)	RARARARGRARBALOX5NR1H4
	SCHEMBL2071380	0.72	RARA (0.48)	RARARARGRARBALOX5NR1H4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.