Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
| ▸ | GABRE | P78334 | 1/20 | 0.45 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.45 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.45 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.45 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15701270 | 0.88 | NAMPT (0.48) | NAMPTHDAC1PTGDR2GRIN2BCYP17A1 | |
| SCHEMBL30684527 | 0.86 | P4HTM (0.48) | NAMPTHDAC1PTGDR2GRIN2BP4HTM | |
| SCHEMBL30684531 | 0.86 | P4HTM (0.48) | NAMPTHDAC1PTGDR2GRIN2BP4HTM | |
| SCHEMBL15354526 | 0.86 | NAMPT (0.50) | NAMPTHDAC1GRIN2BCYP17A1GSK3B | |
| SCHEMBL540536 | 0.86 | NAMPT (0.50) | NAMPTHDAC1PTGDR2GRIN2BCYP17A1 | |
| SCHEMBL164105 | 0.84 | HDAC1 (0.52) | NAMPTHDAC1GRIN2BCYP17A1GSK3B | |
| SCHEMBL9980800 | 0.84 | NAMPT (0.49) | NAMPTHDAC1PTGDR2GRIN2BCYP17A1 | |
| SCHEMBL21394710 | 0.84 | NAMPT (0.49) | NAMPTHDAC1PTGDR2GRIN2BCYP17A1 | |
| SCHEMBL540467 | 0.84 | NAMPT (0.49) | NAMPTHDAC1PTGDR2GRIN2BCYP17A1 | |
| SCHEMBL29523504 | 0.84 | HDAC1 (0.52) | NAMPTHDAC1GRIN2BCYP17A1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278456-A2 | PYRIMIDINE-COMPLIANT PEPTIDE NUCLEIC ACID COMPOSITIONS AND METHODS OF USE THEREOF | NEUBASE THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |
| US-10385100-B2 | Compositions and methods for recognition of RNA using triple helix forming peptide nucleic acids | The Research Foundation for the State University o (US) | 2019-08-20 | — | — | US | disclosed |
| US-10385100-B2 | Compositions and methods for recognition of RNA using triple helix forming peptide nucleic acids | The Research Foundation for the State University o (US) | 2019-08-20 | — | — | US | disclosed |
| US-10260089-B2 | Compositions and methods for recognition of RNA using triple helical peptide nucleic acids | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 2019-04-16 | — | — | US | disclosed |
| US-10260089-B2 | Compositions and methods for recognition of RNA using triple helical peptide nucleic acids | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 2019-04-16 | — | — | US | disclosed |
| US-20170009280-A1 | COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS | UNIV NEW YORK STATE RES FOUND (US) | 2017-01-12 | — | — | US | disclosed |
| US-20170009280-A1 | COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS | UNIV NEW YORK STATE RES FOUND (US) | 2017-01-12 | — | — | US | disclosed |
| US-20170009280-A1 | COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS | UNIV NEW YORK STATE RES FOUND (US) | 2017-01-12 | — | — | US | disclosed |
| US-20140206838-A1 | COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140206838-A1 | COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-07-24 | — | — | US | disclosed |
| US-20140206838-A1 | COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2014-07-24 | — | — | US | disclosed |
| WO-2010130708-A9 | BETA-LACTAMASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2011-01-13 | — | — | WO | disclosed |
| US-20100292185-A1 | BETA-LACTAMASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD (BM) | 2010-11-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170009280-A1 | COMPOSITIONS AND METHODS FOR RECOGNITION OF RNA USING TRIPLE HELICAL PEPTIDE NUCLEIC ACIDS | TARBP1, TRDMT1, ADAR | NAMPT 830/4885HDAC1 2626/4885PTGDR2 4149/4885 |
| US-10260089-B2 | Compositions and methods for recognition of RNA using triple helical peptide nucleic acids | TARBP1, TRDMT1, ADAR | NAMPT 830/4885HDAC1 2626/4885PTGDR2 4149/4885 |
| US-10385100-B2 | Compositions and methods for recognition of RNA using triple helix forming peptide nucleic acids | TARBP1, TRDMT1, NSUN3 | NAMPT 858/4885HDAC1 3096/4885PTGDR2 4287/4885 |
| US-20100292185-A1 | BETA-LACTAMASE INHIBITORS | GANAB, BPGM, BLVRB | NAMPT 827/4885HDAC1 3077/4885PTGDR2 3845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.