Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626223 | 0.78 | CYP2C19 (0.46) | SMN1; SMN2LMNARAB9ACYP2C19NPC1 | |
| SCHEMBL7900084 | 0.76 | MAOA (0.42) | MAOAMAOBMAPTALDH1A1 | |
| SCHEMBL824471 | 0.76 | ALDH1A1 (0.66) | SMN1; SMN2LMNARAB9ACYP2C19NPC1 | |
| SCHEMBL7900060 | 0.76 | ALDH1A1 (0.66) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MAOA | |
| SCHEMBL711309 | 0.74 | CYP2C19 (0.52) | SMN1; SMN2LMNARAB9ACYP2C19NPC1 | |
| SCHEMBL7892776 | 0.74 | CYP1A2 (0.47) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL291657 | 0.73 | CYP2C19 (0.48) | SMN1; SMN2LMNARAB9ACYP2C19NPC1 | |
| SCHEMBL6471170 | 0.73 | CYP2C19 (0.46) | SMN1; SMN2LMNARAB9ACYP2C19NPC1 | |
| SCHEMBL9786192 | 0.72 | MAOA (0.47) | SMN1; SMN2LMNAMAOAMAOBMAPT | |
| SCHEMBL499117 | 0.72 | CYP2C19 (0.64) | SMN1; SMN2RAB9ACYP2C19NPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351332-B1 | HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | RHONE-POULENC AGROCHIMIE (FR) | 1993-03-24 | — | — | EP | disclosed |
| US-5123953-A | DIHALOGENATED HERBICIDAL SULPHONES | RHONE-POULENC AGROCHIMIE (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5100460-A | HERBICIDAL COMPOUNDS AND COMPOSITIONS CONTAINING THEM | RHONE-POULENC AGROCHIMIE (FR) | 1992-03-31 | — | — | US | disclosed |
| EP-0398818-A1 | Dihalogenated herbicidal sulfones | RHONE-POULENC AGROCHIMIE (FR) | 1990-11-22 | — | — | EP | disclosed |
| CN-1039805-A | Herbicidal compound and composition thereof | RHONE POULENC AGROCHIMIE (FR) | 1990-02-21 | — | — | CN | disclosed |
| EP-0351332-A1 | Herbicidal compounds and compositions containing them | RHONE-POULENC AGROCHIMIE (FR) | 1990-01-17 | — | — | EP | disclosed |