Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129642 | 0.88 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1PKMNPBWR1 | |
| SCHEMBL15224297 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1PKMNPBWR1 | |
| SCHEMBL14902207 | 0.82 | ALDH1A1 (0.54) | ALDH1A1KMT2AMEN1PKMNPBWR1 | |
| SCHEMBL28230970 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KMT2AMEN1NPSR1KDM4E | |
| SCHEMBL15016380 | 0.81 | ALDH1A1 (0.53) | ALDH1A1KMT2AMEN1PKMNPBWR1 | |
| SCHEMBL19668292 | 0.80 | KMT2A (0.45) | ALDH1A1KMT2APKMKDM4EL3MBTL1 | |
| SCHEMBL7080112 | 0.80 | KMT2A (0.41) | ALDH1A1KMT2AMEN1NPSR1PHGDH | |
| SCHEMBL4145907 | 0.80 | ALDH1A1 (0.56) | ALDH1A1KMT2AMEN1PKMNPBWR1 | |
| SCHEMBL10723835 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KMT2AMEN1PKMNPBWR1 | |
| Magnesium SCHEMBL29521337 | 0.78 | KMT2A (0.40) | ALDH1A1KMT2AMEN1PKMNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8822452-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2014-09-02 | — | — | US | disclosed |
| US-20130303522-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-11-14 | — | — | US | disclosed |
| US-8524894-B2 | Inhibitor compounds of 11-beta-hydroxysteroid dehydrogenase type 1 | LABORATORIOS SALVAT, S.A. (ES) | 2013-09-03 | — | — | US | disclosed |
| EP-0333080-B1 | BETA-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-10-13 | — | — | EP | disclosed |
| US-5206254-A | Antitussive agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1993-04-27 | — | — | US | disclosed |
| EP-0407403-A1 | BETA-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES | BOEHRINGER BIOCHEMIA ROBIN S.p.A. (IT) | 1991-01-16 | — | — | EP | disclosed |
| WO-1989008648-A1 | beta-CARBONYL-CARBOXYAMIDES OF 1,3-THIAZOLIDINES | BOEHRINGER BIOCHEMIA ROBIN S.P.A. (IT) | 1989-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303522-A1 | INHIBITOR COMPOUNDS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | HSD11B1, HSD17B1, HSD11B2 | ALDH1A1 144/4885KMT2A 3868/4885MEN1 827/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.