Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAP2K7 | O14733 | 3/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10519387 | 0.80 | P2RX7 (0.41) | GSTO1MAP2K7AURKAP2RX7BTK | |
| SCHEMBL9494566 | 0.77 | ALDH1A1 (0.66) | ALDH1A1 | |
| SCHEMBL8515102 | 0.75 | RAB9A (0.49) | RAB9AALDH1A1HPGDSPDE4APDE4B | |
| SCHEMBL9494557 | 0.72 | KMT2A (0.45) | GSTO1ALDH1A1BTK | |
| SCHEMBL12985200 | 0.72 | RAB9A (0.50) | RAB9AALDH1A1HPGDSPDE4APDE4B | |
| SCHEMBL9492592 | 0.72 | CYP1A2 (0.52) | RAB9AP2RX7ALDH1A1 | |
| SCHEMBL4772689 | 0.71 | DHODH (0.53) | ALDH1A1 | |
| SCHEMBL17055639 | 0.71 | PDE4A (0.48) | RAB9AALDH1A1HPGDSPDE4APDE4B | |
| SCHEMBL9609104 | 0.68 | RAB9A (0.43) | RAB9AALDH1A1HPGDSPDE4APDE4B | |
| SCHEMBL26909718 | 0.68 | MTNR1A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345573-B1 | 2-[(Meth)acrylamidomethyl]-1,3-diketones | BASF Aktiengesellschaft (DE) | 1993-04-21 | — | — | EP | disclosed |
| EP-0345638-B1 | 4-[(Meth)acrylamidomethyl] pyrazoles and isoxazoles, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1992-09-16 | — | — | EP | disclosed |
| US-5015768-A | Reaction of diketone with methylol(meth)acrylamide by dehydration | BASF AKTIENGESELLSCHAFT (DE) | 1991-05-14 | — | — | US | disclosed |
| US-5011991-A | 2-((meth)acrylamidomethyl)-1,3-diketones | BASF AKTIENGESELLSCHAFT (DE) | 1991-04-30 | — | — | US | disclosed |
| US-4946917-A | 4-[(meth)acrylamidomethyl]-pyrazoles and -isoxazoles, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1990-08-07 | — | — | US | disclosed |
| US-4939268-A | 4-(meth)acrylamidomethyl)-pyrazoles and -isoxazoles, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1990-07-03 | — | — | US | disclosed |
| EP-0345638-A1 | 4-[(Meth)acrylamidomethyl] pyrazoles and isoxazoles, process for their preparation and their use | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |
| EP-0345573-A2 | 2-[(Meth)acrylamidomethyl]-1,3-diketones | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |
| EP-0345636-A2 | Light-sensitive negative lithographic printing plates | BASF Aktiengesellschaft (DE) | 1989-12-13 | — | — | EP | disclosed |