Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | GRM4 | Q14833 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 2/20 | 0.42 |
| ▸ | STK17B | O94768 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248909 | 0.82 | NPC1 (0.59) | GRM4RAB9ANPC1HPGDHTT | |
| SCHEMBL9839204 | 0.79 | NPSR1 (0.52) | NPSR1GRM4MEN1KMT2AMAPT | |
| SCHEMBL5252795 | 0.78 | DHODH (0.51) | NPSR1GRM4MEN1KMT2AMAPT | |
| SCHEMBL11731664 | 0.77 | EGFR (0.46) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL11732793 | 0.77 | GRM4 (0.52) | NPSR1GRM4KMT2AMAPTRAB9A | |
| SCHEMBL9497949 | 0.77 | LMNA (0.59) | GRM4RAB9ABRAFHTT | |
| SCHEMBL9494044 | 0.74 | RAB9A (0.64) | NPSR1GRM4MEN1KMT2AMAPT | |
| SCHEMBL9494146 | 0.73 | ABCG2 (0.51) | GRM4MEN1KMT2AMAPTRAB9A | |
| SCHEMBL25341628 | 0.73 | NPSR1 (0.54) | NPSR1GRM4MEN1KMT2AMAPT | |
| SCHEMBL7765065 | 0.72 | HDAC3 (0.55) | NPSR1GRM4MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264437-A | Antiinflammatory agents, immunosuppressants or antiallergens | SYNTEX (U.S.A.) INC. (US) | 1993-11-23 | — | — | US | disclosed |