Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684154 | 0.87 | BCHE (0.42) | BCHE | |
| SCHEMBL9685558 | 0.87 | BCHE (0.42) | BCHE | |
| SCHEMBL9685612 | 0.87 | BCHE (0.42) | BCHE | |
| SCHEMBL9497399 | 0.86 | SMN1; SMN2 (0.41) | BCHETDP1L3MBTL1 | |
| SCHEMBL9577155 | 0.86 | SMN1; SMN2 (0.41) | BCHETDP1L3MBTL1 | |
| SCHEMBL17006171 | 0.85 | LTA4H (0.38) | BCHETDP1 | |
| SCHEMBL9685275 | 0.85 | KCNA3 (0.43) | BCHE | |
| SCHEMBL16177752 | 0.84 | BCHE (0.39) | BCHETDP1L3MBTL1 | |
| SCHEMBL1776277 | 0.82 | SMN1; SMN2 (0.43) | BCHETDP1L3MBTL1 | |
| SCHEMBL15602691 | 0.81 | SMN1; SMN2 (0.38) | MAPTBCHETDP1L3MBTL1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145844-A | Enzyme inhibitors, antiinflammatory agents, analgesics | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-09-08 | — | — | US | disclosed |
| US-5030733-A | Analgesics, antiinflammatory agents, phospholipase inhibitor | HOECHST-ROUSSEL PHARMACETICALS INCORPORATED (US) | 1991-07-09 | — | — | US | disclosed |
| EP-0300397-A2 | Hydroxy-, Alkoxy- and Benzyloxy substituted phospholipids, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1989-01-25 | — | — | EP | disclosed |