SCHEMBL9497451

SCHEMBL9497451

CCN(CCO[Si](C)(C)C(C)(C)C)c1ccc(C=O)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.54
ALDH1A3 P47895 2/20 0.54
ALDH3A1 P30838 2/20 0.54
KDM4E B2RXH2 3/20 0.42
GAA P10253 3/20 0.42
MAPT P10636 8/20 0.40
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
CYP2A6 P11509 1/20 0.38
CYP2A13 Q16696 1/20 0.38
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
L3MBTL1 Q9Y468 2/20 0.36
HTT P42858 1/20 0.36
LMNA P02545 2/20 0.35
HPGD P15428 2/20 0.35
GFER P55789 2/20 0.35
GLA P06280 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CNR2 P34972 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1234774 0.94 ALDH1A1 (0.49) ALDH1A1ALDH1A3ALDH3A1KDM4EGAA
SCHEMBL12422405 0.84 CYP2A6 (0.42) ALDH1A1ALDH1A3ALDH3A1KDM4EMAPT
SCHEMBL14444968 0.80 ALDH1A1 (0.36) ALDH1A1ALDH1A3ALDH3A1KDM4EGAA
SCHEMBL5371036 0.80 ALDH1A1 (0.36) ALDH1A1ALDH1A3ALDH3A1KDM4EGAA
SCHEMBL98656 0.80 ALDH1A1 (0.34) ALDH1A1ALDH1A3ALDH3A1KDM4EGAA
SCHEMBL16446031 0.79 ALDH1A1 (0.34) ALDH1A1ALDH1A3ALDH3A1KDM4EGAA
SCHEMBL6129301 0.79 ALOX5 (0.38) ALDH1A1KDM4EGAAMAPTNPC1
SCHEMBL10938401 0.77 ALDH1A1 (0.67) ALDH1A1ALDH1A3ALDH3A1KDM4EGAA
SCHEMBL14418353 0.77 LMNA (0.34) ALDH1A1KDM4EGAAMAPTMEN1
SCHEMBL6933156 0.77 DUT (0.33) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160194417-A1 DEGRADABLE POLYMER RESINS AND METHODS FOR THEIR PREPARATION EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2016-07-07 US disclosed
WO-2015020646-A1 DEGRADABLE POLYMER RESINS AND METHODS FOR THEIR PREPARATION EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) 2015-02-12 WO disclosed
US-5256784-A Merocyanine dyes MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-26 US disclosed