Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 2/20 | 0.42 |
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14542091 | 1.00 | S1PR3 (0.51) | S1PR3POLBTSHRMAPTTHRB | |
| SCHEMBL4540961 | 0.88 | S1PR3 (0.54) | S1PR3POLBTSHRMAPTTHRB | |
| SCHEMBL4528105 | 0.88 | S1PR3 (0.54) | S1PR3POLBTSHRMAPTTHRB | |
| SCHEMBL4528057 | 0.88 | S1PR3 (0.54) | S1PR3POLBTSHRMAPTTHRB | |
| SCHEMBL22435423 | 0.83 | TSHR (0.43) | POLBTSHRMAPTGAAALDH1A1 | |
| SCHEMBL28313554 | 0.83 | MAPT (0.41) | S1PR3POLBTSHRMAPTTHRB | |
| SCHEMBL25045972 | 0.83 | MEN1 (0.48) | POLBTSHRMAPTNPSR1SMN1; SMN2 | |
| SCHEMBL4539460 | 0.82 | POLB (0.51) | S1PR3POLBTSHRMAPTTHRB | |
| SCHEMBL7525322 | 0.82 | L3MBTL1 (0.42) | POLBTSHRMAPTALDH1A1NPSR1 | |
| Methane SCHEMBL18477986 | 0.81 | S1PR3 (0.47) | S1PR3POLBTSHRMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5208223-A | Enzyme inhibitors | AMERICAN CYANAMID COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5144045-A | Treatment of inflammatory related disorders | AMERICAN CYANAMID COMPANY (US) | 1992-09-01 | — | — | US | disclosed |