Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.52 |
| ▸ | NPC1 | O15118 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.52 |
| ▸ | RELA | Q04206 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498768 | 0.96 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9500177 | 0.95 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9500282 | 0.95 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9500862 | 0.95 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9500068 | 0.95 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9500839 | 0.95 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9499176 | 0.92 | SMN1; SMN2 (0.44) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9498680 | 0.86 | NPC1 (0.41) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9498428 | 0.84 | RARB (0.40) | RAB9ANPC1SMN1; SMN2NFKB1NFKB2 | |
| SCHEMBL9500172 | 0.82 | CYP2D6 (0.40) | RAB9ANPC1SMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |