Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TTPA | P49638 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499474 | 0.91 | MEN1 (0.35) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9499270 | 0.84 | MEN1 (0.36) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9497848 | 0.81 | MEN1 (0.40) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9500139 | 0.80 | EPHX1 (0.38) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9498097 | 0.77 | MEN1 (0.35) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9500067 | 0.74 | KDM4C (0.49) | MEN1KMT2AKDM4EMAPT | |
| Fumaric Acid SCHEMBL9795052 | 0.74 | MEN1 (0.36) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9501618 | 0.72 | KDM4E (0.37) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL9499578 | 0.70 | MEN1 (0.37) | MEN1CYP2C9ALOX15CYP2C19KMT2A | |
| SCHEMBL2417145 | 0.70 | MEN1 (0.44) | MEN1CYP2C9ALOX15CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |