Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 5/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498097 | 0.86 | MEN1 (0.35) | KDM4CEPHX1MEN1KMT2APOLB | |
| SCHEMBL9499474 | 0.83 | MEN1 (0.35) | EPHX1MEN1KMT2APOLBKDM4E | |
| SCHEMBL20381102 | 0.83 | NPC1 (0.40) | KDM4CEPHX1MEN1KMT2ALMNA | |
| SCHEMBL9499270 | 0.79 | MEN1 (0.36) | KDM4CMEN1KMT2AKDM4EMAPT | |
| SCHEMBL9501618 | 0.77 | KDM4E (0.37) | EPHX1MEN1KMT2APOLBKDM4E | |
| SCHEMBL9500139 | 0.76 | EPHX1 (0.38) | EPHX1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL13979236 | 0.76 | PTGS2 (0.36) | EPHX1MEN1KMT2ATSHR | |
| SCHEMBL9498550 | 0.74 | MEN1 (0.37) | MEN1KMT2AKDM4EMAPT | |
| SCHEMBL9795257 | 0.72 | EPHX1 (0.33) | EPHX1KDM4EMAPT | |
| SCHEMBL20381100 | 0.71 | TDP1 (0.54) | EPHX1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| EP-0367019-A1 | Pharmaceutical compositions containing nitroxyalkyl amine with an amide function, and method for the preparation of the compounds | Roche Diagnostics GmbH (DE) | 1990-05-09 | — | — | EP | disclosed |