Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499270 | 0.93 | MEN1 (0.36) | MEN1KMT2AKDM4EMAPTKDM4C | |
| SCHEMBL9500067 | 0.86 | KDM4C (0.49) | MEN1KMT2AEPHX1KDM4EMAPT | |
| SCHEMBL9499474 | 0.86 | MEN1 (0.35) | MEN1KMT2AEPHX1KDM4EMAPT | |
| SCHEMBL9501618 | 0.79 | KDM4E (0.37) | MEN1KMT2AEPHX1KDM4EMAPT | |
| SCHEMBL20381102 | 0.79 | NPC1 (0.40) | MEN1KMT2AEPHX1MAPTALDH1A1 | |
| SCHEMBL9500139 | 0.78 | EPHX1 (0.38) | MEN1KMT2AEPHX1KDM4EMAPT | |
| SCHEMBL9498550 | 0.77 | MEN1 (0.37) | MEN1KMT2AKDM4EMAPTCYP2C9 | |
| SCHEMBL13979236 | 0.75 | PTGS2 (0.36) | MEN1KMT2AEPHX1PTGS1PTGS2 | |
| SCHEMBL20381100 | 0.73 | TDP1 (0.54) | MEN1KMT2AEPHX1 | |
| Fumaric Acid SCHEMBL9795259 | 0.72 | PDE5A (0.37) | MEN1KMT2AKDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |