Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA4 | P22748 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9498550 | 0.91 | MEN1 (0.37) | MEN1KMT2AKDM4EMAPTCYP2C9 | |
| SCHEMBL9498097 | 0.86 | MEN1 (0.35) | MEN1KMT2AEPHX1KDM4EMAPT | |
| SCHEMBL9500067 | 0.83 | KDM4C (0.49) | MEN1KMT2AEPHX1KDM4EMAPT | |
| SCHEMBL9501618 | 0.82 | KDM4E (0.37) | MEN1KMT2AEPHX1KDM4EMAPT | |
| SCHEMBL9499926 | 0.80 | CA12 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2CA12 | |
| SCHEMBL9499270 | 0.78 | MEN1 (0.36) | MEN1KMT2AKDM4EMAPTCYP2C9 | |
| SCHEMBL20381102 | 0.76 | NPC1 (0.40) | MEN1KMT2AEPHX1MAPTALDH1A1 | |
| Fumaric Acid SCHEMBL9795259 | 0.75 | PDE5A (0.37) | MEN1KMT2AKDM4EMAPTALDH1A1 | |
| SCHEMBL9500139 | 0.75 | EPHX1 (0.38) | MEN1KMT2AEPHX1KDM4EMAPT | |
| SCHEMBL9795257 | 0.74 | EPHX1 (0.33) | EPHX1KDM4EMAPTCA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0367019-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING NITROXYALKYL AMINE WITH AN AMIDE FUNCTION, AND METHOD FOR THE PREPARATION OF THE COMPOUNDS | Roche Diagnostics GmbH (DE) | 1993-05-12 | — | — | EP | disclosed |
| US-5037849-A | For treatment of heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1991-08-06 | — | — | US | disclosed |