Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22745804 | 0.86 | MAPT (0.36) | CYP1A2CYP2C19BAZ2BBAZ2AMAPT | |
| SCHEMBL9423183 | 0.84 | ALDH1A1 (0.36) | CYP1A2BAZ2BBAZ2AMAPTLMNA | |
| SCHEMBL9468954 | 0.81 | MAPT (0.35) | CYP1A2BAZ2BBAZ2AMAPTLMNA | |
| SCHEMBL9350427 | 0.80 | NOTUM (0.40) | CYP1A2MAPTHPGDSMN1; SMN2CYP2C9 | |
| SCHEMBL9567022 | 0.80 | TSHR (0.35) | CYP1A2BAZ2BBAZ2AMAPTHPGD | |
| SCHEMBL9351415 | 0.79 | BAZ2B (0.33) | CYP1A2CYP2C19BAZ2BBAZ2AMAPT | |
| SCHEMBL6553643 | 0.79 | BAZ2B (0.38) | CYP1A2CYP2C19BAZ2BBAZ2AMAPT | |
| SCHEMBL9350650 | 0.79 | GAA (0.33) | CYP1A2BAZ2BBAZ2AMAPTLMNA | |
| SCHEMBL9521057 | 0.79 | GAA (0.38) | CYP1A2BAZ2BBAZ2AMAPTLMNA | |
| SCHEMBL7547124 | 0.78 | CYP1A2 (0.33) | CYP1A2BAZ2BBAZ2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0344232-B1 | 3-ARYLURACILS FOR KILLING WEEDS | CIBA-GEIGY AG (CH) | 1993-03-24 | — | — | EP | disclosed |
| US-5041156-A | 3-aryluracils for the control of weeds | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| WO-1989003825-A1 | HETEROCYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE & CO. AKTIENGESELLSCHAFT (CH) | 1989-05-05 | — | — | WO | disclosed |