Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 3/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL948614 | 0.93 | ACHE (0.44) | OPRM1CHRM2CHRM3KCNH2UBE2M | |
| SCHEMBL948166 | 0.91 | OPRM1 (0.39) | OPRM1CHRM2CHRM3KCNH2UBE2M | |
| SCHEMBL949606 | 0.89 | OPRM1 (0.39) | OPRM1CHRM2CHRM3KCNH2UBE2M | |
| SCHEMBL949385 | 0.86 | SIGMAR1 (0.41) | OPRM1CHRM2CHRM3KCNH2UBE2M | |
| SCHEMBL6220319 | 0.80 | DCUN1D1 (0.51) | OPRM1CHRM2CHRM3KCNH2UBE2M | |
| SCHEMBL947328 | 0.80 | OPRM1 (0.43) | OPRM1CHRM2CHRM3KCNH2UBE2M | |
| SCHEMBL948992 | 0.76 | UBE2M (0.48) | OPRM1CHRM2CHRM3KCNH2UBE2M | |
| SCHEMBL948316 | 0.76 | OPRM1 (0.46) | OPRM1CHRM2CHRM3KCNH2SIGMAR1 | |
| SCHEMBL949666 | 0.74 | OPRM1 (0.37) | OPRM1CHRM2CHRM3KCNH2SIGMAR1 | |
| SCHEMBL6218807 | 0.73 | UBE2M (0.49) | OPRM1CHRM2CHRM3KCNH2UBE2M |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004736-A1 | Imidazole derivative, process for producing the same, and use | HRH4, F2, HRH2 | OPRM1 64/4885CHRM2 576/4885CHRM3 1166/4885 |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | F2, H1-3, CYC1 | OPRM1 90/4885CHRM2 1002/4885CHRM3 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.