Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.44 |
| ▸ | RAB9A | P51151 | 8/20 | 0.44 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 4/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 4/20 | 0.42 |
| ▸ | RELA | Q04206 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500477 | 0.92 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL9498768 | 0.91 | RAB9A (0.50) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL9500282 | 0.90 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL9500177 | 0.90 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL9500839 | 0.90 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL9500862 | 0.90 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL9500068 | 0.90 | RAB9A (0.52) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL9498680 | 0.89 | NPC1 (0.41) | SMN1; SMN2RAB9ANPC1TP53NFKB1 | |
| SCHEMBL9500363 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2RAB9ANPC1TP53GAA | |
| SCHEMBL9502022 | 0.81 | CCR1 (0.44) | SMN1; SMN2RAB9ANPC1TP53NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |