Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.37 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499176 | 0.89 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2PDCD1CD274 | |
| SCHEMBL9500477 | 0.86 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9498768 | 0.85 | RAB9A (0.50) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9500177 | 0.84 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9500862 | 0.84 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9500282 | 0.84 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9500068 | 0.84 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9500839 | 0.84 | RAB9A (0.52) | NPC1RAB9ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9502022 | 0.84 | CCR1 (0.44) | NPC1RAB9ASMN1; SMN2PDCD1CD274 | |
| SCHEMBL9498396 | 0.82 | LMNA (0.38) | NPC1RAB9ASMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0354655-B1 | 1-PHENYL-1-PROPANOL DERIVATIVES | CHISSO CORPORATION (JP) | 1993-04-07 | — | — | EP | disclosed |
| US-5076947-A | Optically active; free from temperature dependence | CHISSO CORPORATION (JP) | 1991-12-31 | — | — | US | disclosed |
| EP-0354655-A2 | 1-Phenyl-1-propanol derivatives | CHISSO CORPORATION (JP) | 1990-02-14 | — | — | EP | disclosed |