Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9496620 | 0.89 | AGTR1 (0.36) | AGTR1AGTR2ABCG2CRHR1 | |
| SCHEMBL9494067 | 0.84 | AGTR1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL9494444 | 0.82 | AGTR1 (0.41) | AGTR1AGTR2ABCG2 | |
| SCHEMBL9499272 | 0.79 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9495019 | 0.79 | AGTR1 (0.41) | AGTR1AGTR2ABCG2 | |
| SCHEMBL9494917 | 0.76 | AGTR1 (0.37) | AGTR1AGTR2 | |
| SCHEMBL9494765 | 0.75 | AGTR1 (0.40) | AGTR1AGTR2ABCG2 | |
| SCHEMBL9495733 | 0.75 | AGTR1 (0.40) | AGTR1AGTR2ABCG2 | |
| SCHEMBL4638846 | 0.75 | ABCG2 (0.46) | AGTR1AGTR2ABCG2 | |
| SCHEMBL30743612 | 0.73 | ABCG2 (0.55) | AGTR1ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5236937-A | Treating hypertension, congestive heart failure | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-08-17 | — | — | US | disclosed |