Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779327 | 0.72 | ALDH1A1 (0.43) | LMNA | |
| SCHEMBL3293711 | 0.72 | LMNA (0.46) | LMNA | |
| SCHEMBL9500935 | 0.71 | ALDH1A1 (0.38) | LMNA | |
| SCHEMBL9452666 | 0.68 | — | — | |
| SCHEMBL25290444 | 0.67 | — | — | |
| SCHEMBL9505491 | 0.66 | ALDH1A1 (0.37) | LMNA | |
| SCHEMBL27843636 | 0.65 | HSD17B10 (0.36) | — | |
| SCHEMBL18665450 | 0.64 | — | — | |
| SCHEMBL8362152 | 0.64 | — | — | |
| Bromomethane SCHEMBL27762402 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373759-B1 | COMPOUND, COMPOSITION, PROCESS AND USE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-09 | — | — | EP | claimed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | claimed |
| EP-0373759-B1 | COMPOUND, COMPOSITION, PROCESS AND USE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-09 | — | — | EP | disclosed |
| US-5112871-A | ANTI-MICROBIAL BROMO-NITRO COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |