Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499558 | 0.81 | NAAA (0.40) | ALDH1A1GAALMNAKMT2A | |
| SCHEMBL5576745 | 0.80 | LMNA (0.37) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL10895703 | 0.80 | ALDH1A1 (0.40) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL10965610 | 0.76 | GALR3 (0.39) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL10897522 | 0.73 | ALDH1A1 (0.34) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL11528628 | 0.72 | LMNA (0.37) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL1434500 | 0.72 | LMNA (0.46) | ALDH1A1CHRM5CHRM1CHRM3PGR | |
| SCHEMBL3293711 | 0.71 | LMNA (0.46) | ALDH1A1TSHRLMNA | |
| SCHEMBL9499560 | 0.71 | LMNA (0.31) | LMNA | |
| Debropol SCHEMBL28989479 | 0.70 | LMNA (0.37) | ALDH1A1LMNATP53MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0373759-B1 | COMPOUND, COMPOSITION, PROCESS AND USE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-09 | — | — | EP | claimed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | claimed |
| EP-0373759-B1 | COMPOUND, COMPOSITION, PROCESS AND USE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-09 | — | — | EP | disclosed |
| US-5112871-A | ANTI-MICROBIAL BROMO-NITRO COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-12 | — | — | US | disclosed |
| EP-0373759-A1 | Compound, composition, process and use | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-06-20 | — | — | EP | disclosed |