Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500899 | 0.82 | BRD4 (0.41) | GRM5RAB9A | |
| SCHEMBL9027236 | 0.79 | FFAR1 (0.40) | GRM5RAB9A | |
| SCHEMBL8777792 | 0.78 | APP (0.41) | GRM5GPR52HTR2CHTR2BHTR2A | |
| SCHEMBL9025837 | 0.76 | GRM5 (0.43) | GRM5RAB9A | |
| SCHEMBL2666275 | 0.74 | KMO (0.48) | RAB9A | |
| SCHEMBL21977980 | 0.72 | IDH1 (0.51) | — | |
| SCHEMBL2128638 | 0.72 | ALDH1A1 (0.50) | HTR2CHTR2BHTR2ANR3C2RAB9A | |
| SCHEMBL30047602 | 0.72 | ALDH1A1 (0.50) | HTR2CHTR2BHTR2ANR3C2RAB9A | |
| SCHEMBL9025927 | 0.72 | GRM5 (0.38) | GRM5LTA4HTLR8TLR7MPO | |
| SCHEMBL9550832 | 0.71 | CCR1 (0.43) | GRM5RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0459662-B1 | Fungicidal compounds | ZENECA LTD (GB) | 1996-08-21 | — | — | EP | disclosed |
| US-5185339-A | FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-02-09 | — | — | US | disclosed |
| EP-0459662-A1 | Fungicidal compounds | ZENECA LIMITED (GB) | 1991-12-04 | — | — | EP | disclosed |