Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9500898 | 0.87 | JAK2 (0.35) | NISCH | |
| Propylene Oxide SCHEMBL9498943 | 0.81 | — | — | |
| SCHEMBL11284485 | 0.63 | CYP11B2 (0.43) | — | |
| SCHEMBL19526135 | 0.61 | LMNA (0.36) | — | |
| SCHEMBL6674432 | 0.61 | GDA (0.38) | BRD4ALDH1A1 | |
| SCHEMBL20011085 | 0.61 | GDA (0.32) | ALDH1A1 | |
| SCHEMBL1772622 | 0.60 | KDM4E (0.43) | BRD4KDM4EALDH1A1 | |
| SCHEMBL20182463 | 0.60 | TNKS2 (0.32) | — | |
| SCHEMBL2197993 | 0.60 | MAOA (0.53) | GAANPSR1 | |
| SCHEMBL310818 | 0.59 | ALDH1A1 (0.42) | KDM4EGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5270465-A | 4(3H)-pteridinone compounds | LIPHA, LYONNAISE INDUSTRILLE PHARMACEUTIQUE (FR) | 1993-12-14 | — | — | US | claimed |