Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | SLC26A6 | Q9BXS9 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9502803 | 0.82 | HIF1A (0.39) | SMN1; SMN2KDM4ERAB9ANPC1HTT | |
| SCHEMBL9263418 | 0.73 | ALDH1A1 (0.44) | SMN1; SMN2KDM4ERAB9ANPSR1TP53 | |
| SCHEMBL1349347 | 0.72 | MGAM (0.47) | SMN1; SMN2KDM4ERAB9ANPSR1TP53 | |
| SCHEMBL5502158 | 0.71 | MEN1 (0.43) | SMN1; SMN2KDM4ENPSR1NLRP3KMT2A | |
| SCHEMBL9500955 | 0.69 | TSPO (0.43) | SMN1; SMN2KDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL9046771 | 0.69 | KDM4E (0.41) | SMN1; SMN2KDM4ETDP1L3MBTL1NLRP3 | |
| SCHEMBL29692244 | 0.69 | PTPN1 (0.56) | SMN1; SMN2KDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL312900 | 0.69 | PTPN1 (0.56) | SMN1; SMN2KDM4ERAB9ANPC1NPSR1 | |
| SCHEMBL7005186 | 0.68 | LMNA (0.41) | SMN1; SMN2KDM4ERAB9ANPC1L3MBTL1 | |
| SCHEMBL31439627 | 0.67 | PTPN1 (0.54) | SMN1; SMN2KDM4ERAB9ANPC1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0312085-B1 | NOVEL QUINOLINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND ANTIBACTERIAL AGENT CONTAINING THEM | Dainippon Pharmaceutical Co., Ltd. (JP) | 1993-05-12 | — | — | EP | disclosed |
| US-5164392-A | Active against streptococci and staphylococci | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1992-11-17 | — | — | US | disclosed |
| US-5013841-A | Oxo quinoline derivatives | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0312085-A2 | Novel quinoline derivatives, processes for preparation thereof and antibacterial agent containing them | Dainippon Pharmaceutical Co., Ltd. (JP) | 1989-04-19 | — | — | EP | disclosed |