Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.56 |
| ▸ | FEN1 | P39748 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29692244 | 1.00 | PTPN1 (0.56) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL31439627 | 0.98 | PTPN1 (0.54) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL8634975 | 0.88 | KDM4E (0.47) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL2465379 | 0.87 | NLRP3 (0.51) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL26673364 | 0.85 | CTNNB1 (0.51) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL28823305 | 0.84 | NLRP3 (0.49) | ERCC5FEN1NPC1RAB9AKDM4E | |
| SCHEMBL3692544 | 0.84 | PTPN1 (0.61) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL30395419 | 0.84 | PTPN1 (0.61) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL1739431 | 0.84 | ERCC5 (0.61) | PTPN1ERCC5FEN1NPC1RAB9A | |
| SCHEMBL30271604 | 0.84 | ERCC5 (0.61) | PTPN1ERCC5FEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 364 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260070922-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | HAGER BIOSCIENCES, LLC (US) | 2026-03-12 | — | — | US | disclosed |
| US-20250345441-A1 | ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME | UNIV YALE (US) | 2025-11-13 | — | — | US | disclosed |
| US-20250276067-A1 | ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME | UNIV YALE (US) | 2025-09-04 | — | — | US | disclosed |
| EP-4580620-A2 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS, COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | Hager Biosciences, LLC (US) | 2025-07-09 | — | — | EP | disclosed |
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | MRJA THERAPEUTICS, INC. | 2025-05-08 | — | — | US | disclosed |
| WO-2024050061-A2 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS, COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | HAGER BIOSCIENCES, LLC (US) | 2024-03-07 | — | — | WO | disclosed |
| CN-117088824-A | Preparation method of alpha-1, 3, 5-triazine thioketone compound | 浙江工业大学 | 2023-11-21 | — | — | CN | disclosed |
| WO-2023201780-A1 | METHOD FOR PREPARING QUINOLONE COMPOUND AND INTERMEDIATE THEREOF | 重庆文理学院 | 2023-10-26 | — | — | WO | disclosed |
| EP-4265621-A1 | PYRROLE DERIVATIVE, AND PREPARATION METHOD AND USE THEREFOR | Shenzhen Sungening Bio-Medical Co., Ltd. (CN) | 2023-10-25 | — | — | EP | disclosed |
| CN-114702443-B | Process for preparing quinolone compounds and intermediates thereof | 重庆文理学院 | 2023-09-19 | — | — | CN | disclosed |
| US-5244892-A | Pseudomonas | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-09-14 | — | — | US | disclosed |
| EP-0538477-A1 | NOVEL CYCLIC AMINOPHENYLACETIC ACID DERIVATIVE, PRODUCTION THEREOF, AND IMMUNE RESPONSE MODULATOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5116404-A | URACIL DERIVATIVES AND PESTICIDES CONTAINING THE SAME AS ACTIVE INGREDIENT | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0481441-A2 | Novel cephem compounds, their preparation processes and antibacterial agents | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1992-04-22 | — | — | EP | disclosed |
| EP-0438209-A1 | Uracil derivatives and pesticides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-07-24 | — | — | EP | disclosed |
| US-4788204-A | TRANQUILIZERS; ANTICONVULSANTS; ANGINA AND IMMUNODIFICIENCY TREATMENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4788199-A | ANXIOLYTICS, ANTICONVULSANTS, ANTIANGINA AGENTS | RHONE-POULENC SANTE (FR) | 1988-11-29 | — | — | US | disclosed |
| US-4728647-A | Amides derived from quinoline, and anxiolytic compositions containing them | RHONE-POULENC SANTE (FR) | 1988-03-01 | — | — | US | disclosed |
| US-4055566-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-4017499-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250345441-A1 | ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME | MTHFD1, DHFR, ABCG2 | PTPN1 4656/4885ERCC5 521/4885FEN1 1193/4885 |
| US-20250276067-A1 | ANTICANCER DRUGS AND METHODS OF MAKING AND USING SAME | MTHFD1, DHFR, ABCG2 | PTPN1 4656/4885ERCC5 521/4885FEN1 1193/4885 |
| US-20250145599-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | IGF1R, IGFBP1, IGFBP2 | PTPN1 1298/4885ERCC5 3996/4885FEN1 3483/4885 |
| US-20260070922-A1 | PYRAZOLE AND IMIDAZOLE DERIVATIVES AS DUAL OREXIN AND KAPPA-OPIOID RECEPTORS MODULATORS COMPOSITION, METHODS FOR TREATING NEUROLOGICAL AND PSYCHIATRIC DISORDERS | OPRK1, OPRD1, HCRTR2 | PTPN1 1957/4885ERCC5 4410/4885FEN1 4780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.