Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11142686 | 0.80 | CCKBR (0.47) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL9501135 | 0.79 | CCKBR (0.64) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL11138052 | 0.78 | CCKBR (0.45) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL11144864 | 0.78 | OPRK1 (0.47) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL10863771 | 0.77 | CCKBR (0.63) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL10865137 | 0.77 | OPRD1 (0.62) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL11006750 | 0.76 | CCKBR (0.49) | CCKBROPRD1OPRK1OPRM1 | |
| Hydrochloric Acid SCHEMBL11167236 | 0.76 | OPRD1 (0.61) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL9531702 | 0.73 | CCKBR (0.67) | CCKBROPRD1OPRK1OPRM1 | |
| SCHEMBL9499795 | 0.73 | CCKBR (0.58) | CCKBROPRD1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5206238-A | Cholecystokinin antagonists | MERCK & CO., INC. (US) | 1993-04-27 | — | — | US | disclosed |
| EP-0486271-A2 | Cholecystokinin antagonists for treating neurological disorders | MERCK & CO. INC. (US) | 1992-05-20 | — | — | EP | disclosed |