SCHEMBL9501236

SCHEMBL9501236

CC(C)(C)c1cc(S(=O)(=O)CO)cc(C(C)(C)C)c1O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.48
CA1 P00915 2/20 0.48
ALDH1A1 P00352 6/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
POLB P06746 1/20 0.47
TYR P14679 1/20 0.47
MEN1 O00255 3/20 0.46
TSHR P16473 3/20 0.46
KMT2A Q03164 3/20 0.46
GABBR2 O75899 3/20 0.46
GABBR1 Q9UBS5 3/20 0.46
MAPK1 P28482 3/20 0.46
LMNA P02545 3/20 0.46
CYP1A2 P05177 3/20 0.46
CYP3A4 P08684 2/20 0.46
BLM P54132 2/20 0.46
ATM Q13315 2/20 0.46
HIF1A Q16665 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
ALOX15 P16050 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13522250 0.79 CA2 (0.56) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL4082532 0.79 ALDH1A1 (0.42) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL9330309 0.79 VCAM1 (0.49) CA2CA1ALDH1A1SMN1; SMN2KMT2A
SCHEMBL1962153 0.78 CA2 (0.54) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL4710701 0.78 CA2 (0.54) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL6858911 0.78 CA2 (0.54) CA2CA1ALDH1A1SMN1; SMN2POLB
Ammonia Solution, Strong SCHEMBL25385967 0.76 CA2 (0.52) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL1960304 0.76 CA2 (0.52) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL4894218 0.76 CA2 (0.52) CA2CA1ALDH1A1SMN1; SMN2POLB
SCHEMBL8768792 0.76 CA2 (0.52) CA2CA1ALDH1A1SMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0539572-A1 LOW-SULFUR DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES The Lubrizol Corporation (US) 1993-05-05 EP disclosed