Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8394386 | 0.81 | MALT1 (0.46) | TP53LMNAPOLBMALT1MAPT | |
| SCHEMBL8394387 | 0.81 | MALT1 (0.46) | TP53LMNAPOLBMALT1MAPT | |
| SCHEMBL8394389 | 0.81 | MALT1 (0.46) | TP53LMNAPOLBMALT1MAPT | |
| SCHEMBL11216515 | 0.78 | CYP19A1 (0.44) | MAPT | |
| SCHEMBL11886204 | 0.78 | DRD2 (0.53) | DRD2DRD3 | |
| SCHEMBL11067202 | 0.77 | TP53 (0.49) | TP53LMNAPOLBMALT1MAPT | |
| SCHEMBL461002 | 0.76 | TP53 (0.45) | TP53LMNAPOLBMALT1MAPT | |
| Hydrochloric Acid SCHEMBL21810865 | 0.76 | TP53 (0.45) | TP53LMNAPOLBMALT1MAPT | |
| SCHEMBL8522066 | 0.75 | CACNA1G (0.39) | TP53LMNAPOLBMAPT | |
| SCHEMBL5239331 | 0.74 | SIGMAR1 (0.49) | TP53LMNAPOLBDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0335375-B1 | ANTIHYPERLIPIDEMIC AND ANTIATHEROSCLEROTIC COMPOUNDS AND COMPOSITIONS | WARNER-LAMBERT COMPANY (US) | 1993-06-09 | — | — | EP | disclosed |
| US-5030653-A | N-2,6-dialkyl- or n-2,6-dialkoxyphenyl-n-arylalkylurea compounds | WARNER-LAMBERT COMPANY (US) | 1991-07-09 | — | — | US | disclosed |
| US-4999373-A | Phenyl ureas or thioureas substituted with a xanthene or thioxanthene group | WARNER-LAMBERT COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| US-4948806-A | N-2,6-DIALKYL-OR N-2,6-DIALKOXYPHENYL-N'-ARYLALKYLUREA | WARNER-LAMBERT COMPANY (US) | 1990-08-14 | — | — | US | disclosed |
| US-4868210-A | PHENYL UREAS AND PHENYL THIOUREAS | WARNER-LAMBERT COMPANY (US) | 1989-09-19 | — | — | US | disclosed |