SCHEMBL950126

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL949381	0.86	THRB (0.36)	THRBTSHRALDH1A1CYP17A1CYP19A1
	SCHEMBL951050	0.85	THRB (0.40)	THRBTSHRALDH1A1CYP17A1CYP19A1
	SCHEMBL950092	0.83	THRB (0.44)	THRBTSHRALDH1A1CYP17A1CYP19A1
	SCHEMBL951391	0.83	THRB (0.32)	THRBCYP17A1CYP19A1
	SCHEMBL10027336	0.82	THRB (0.41)	THRBTSHRALDH1A1CYP17A1CYP19A1
	SCHEMBL8491934	0.80	THRB (0.50)	THRBTSHRALDH1A1CA1CA2
	SCHEMBL10027335	0.78	CYP17A1 (0.42)	THRBTSHRALDH1A1CYP17A1CYP19A1
	SCHEMBL2740753	0.78	CYP17A1 (0.43)	THRBTSHRALDH1A1CYP17A1CYP19A1
	SCHEMBL12263940	0.77	THRB (0.44)	THRBTSHRALDH1A1CA1CA2
	SCHEMBL950282	0.77	ALDH1A1 (0.35)	THRBTSHRALDH1A1CYP17A1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.