Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 5/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | BAX | Q07812 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527140 | 0.92 | SCN4A (0.36) | MAOALTA4HTSHRCA1CA2 | |
| SCHEMBL9507359 | 0.81 | LMNA (0.42) | MAOALTA4HTSHRKMT2A | |
| SCHEMBL326200 | 0.78 | MAOB (0.54) | MAOALTA4HPPARGPPARACA1 | |
| SCHEMBL18920660 | 0.77 | LTA4H (0.47) | MAOALTA4HTSHRNR1H2BAX | |
| SCHEMBL7258661 | 0.76 | ESR2 (0.41) | LTA4HNR1H2BAXCA1CA2 | |
| SCHEMBL9487460 | 0.74 | LTA4H (0.52) | MAOALTA4HTSHRNR1H2BAX | |
| Diphenylether SCHEMBL474226 | 0.71 | LTA4H (0.71) | MAOALTA4HTSHRNR1H2BAX | |
| SCHEMBL6822836 | 0.71 | CA1 (0.37) | MAOALTA4HTSHRPPARGPPARA | |
| SCHEMBL8909407 | 0.71 | CA4 (0.39) | MAOALTA4HTSHR | |
| SCHEMBL366155 | 0.71 | CA4 (0.39) | MAOALTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0412391-B1 | CYCLOPROPANE THIOCARBOXYLIC ACID AMIDES | BASF Aktiengesellschaft (DE) | 1993-09-29 | — | — | EP | claimed |
| EP-0350688-B1 | CYCLOPROPANE CARBOXAMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE TO COMBAT PESTS | BASF Aktiengesellschaft (DE) | 1993-04-14 | — | — | EP | claimed |
| JP-3135953-A | — | — | None | — | — | JP | disclosed |
| JP-H03135953-A | CYCLOPROPANETHIOCARBOXAMIDES | BASF AG | 1991-06-10 | — | — | JP | disclosed |