Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.54 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.38 |
| ▸ | VPS4B | O75351 | 1/20 | 0.38 |
| ▸ | VCP | P55072 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9501139 | 0.73 | SCN5A (0.53) | SCN5ACACNA1BSLC6A3EPHX2 | |
| SCHEMBL9499871 | 0.71 | FDPS (1.00) | FDPS | |
| SCHEMBL9394777 | 0.70 | FDPS (1.00) | FDPS | |
| Bromide SCHEMBL11583932 | 0.69 | SCN5A (0.55) | SCN5ACACNA1BSLC6A3EPHX2VPS4B | |
| SCHEMBL9151249 | 0.69 | FDPS (1.00) | FDPS | |
| SCHEMBL9730756 | 0.68 | FDPS (0.56) | FDPS | |
| SCHEMBL9554607 | 0.68 | LTA4H (0.48) | SCN5ACACNA1BSLC6A3 | |
| SCHEMBL9500738 | 0.67 | FDPS (1.00) | FDPS | |
| SCHEMBL11583277 | 0.67 | HTR2A (0.69) | SCN5ACACNA1BSLC6A3EPHX2 | |
| SCHEMBL7389383 | 0.67 | CACNA1B (0.54) | CACNA1BSLC6A3EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0320455-A1 | Araliphatyl aminoalcane diphosphonic acids | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | claimed |
| EP-0320455-B1 | ARALIPHATYL AMINOALCANE DIPHOSPHONIC ACIDS | CIBA-GEIGY AG (CH) | 1993-06-09 | — | — | EP | disclosed |
| US-5190930-A | Calcium metabolism disorder | CIBA-GEIGY CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5110807-A | Calcium metabolism disorders | CIBA-GEIGY CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0320455-A1 | Araliphatyl aminoalcane diphosphonic acids | CIBA-GEIGY AG (CH) | 1989-06-14 | — | — | EP | disclosed |